February 19, 2015

TKI Famitinib Delays Progression in Advanced Colorectal Cancer

The tyrosine kinase inhibitor famitinib was associated with a significant improvement in progression-free survival among patients with advanced or metastatic colorectal cancer, according to the results […]
February 19, 2015

Baseline AFP Protein Levels Affect Ramucirumab Benefit in HCC

Patients with hepatocellular carcinoma (HCC) may derive greater benefit from treatment with second-line ramucirumab if their baseline alpha-fetoprotein (AFP) levels are greater than 400 ng/mL, according […]
February 19, 2015

Surgery may not be necessary for all rectal cancer patients;

Patients with rectal cancer who completed neoadjuvant therapy with a clinical complete response but did not undergo rectal resection had similar 4-year survival rates as patients […]
February 19, 2015

Vitamin D Levels Linked to Colorectal Cancer Survival

Newly diagnosed metastatic colorectal cancer patients with higher vitamin D levels had better outcomes after treatment with a combination of chemotherapy and targeted therapy. The results […]
February 19, 2015

NAPOLI-1: MM-398 Combo Shows Benefit in Metastatic Pancreatic Cancer

The addition of the novel agent MM-398 to second-line 5-FU/leucovorin extended survival in patients with metastatic pancreatic cancer, according to an expanded analysis of the phase […]
February 19, 2015

Addition of oxaliplatin to FOLFIRI and bevacizumab doubled 5-year survival.

Twice as many patients with metastatic colorectal cancer remained alive after 5 years with a four-drug chemotherapy regimen plus bevacizumab (Avastin) versus three drugs and the […]
February 19, 2015

The 2015 ASCO Gastrointestinal Cancers Symposium

The 2015 ASCO Gastrointestinal Cancers Symposium, held last month in San Francisco, brought together oncology professionals to highlight the latest research and science in cancers of […]
December 12, 2014

Investigational Antibody Demonstrates Efficacy, Safety for Patients with Aggressive Multiple Myeloma in Phase I Study

SAR650984 (SAR) is another anti-CD38 antibody that has shown single-agent activity in Phase I testing among heavily pre-treated myeloma patients. In this Phase Ib trial, researchers […]
December 12, 2014

Carfilzomib Represents Potent, Effective Addition to Standard Multiple Myeloma Therapy in Phase III Study


The recently approved targeted treatment carfilzomib has been shown to help slow or halt the spread of cancer by targeting the mechanisms that control excess proteins […]
December 12, 2014

Brentuximab Vedotin Prolongs Post-Transplant Survival in Hard-to-Treat Lymphoma Patients in 
Phase III Study


The AETHERA Trial: Results of a Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of Brentuximab Vedotin in the Treatment of Patients at Risk of Progression Following Autologous […]
December 12, 2014

Advances in Lymphoma and Multiple Myeloma Treatment Seek to Improve Outcomes for Patients with Hard-To-Treat Disease

New treatment combinations and targeted therapies for lymphoma and multiple myeloma are improving outcomes for vulnerable patient populations with hard-to-treat disease, according to studies presented at […]
December 12, 2014

Novel Strategies Direct Immune System to Attack Recurrent, Hard-To-Treat Blood Cancers

Novel treatments that harness the body’s own immune cells to attack cancer cells demonstrate safe and durable responses in patients with relapsed and treatment-resistant blood cancers, […]