January 25, 2020

Scientists have discovered more about the mysterious role of epigenetics, the study of how genes change, in controlling the way cancers develop. October, 2022

Often called "dark matter", it could alter the way cancer is detected and treated, research from The Institute of Cancer Research suggests.
April 25, 2021

Exploring Emerging IO Combinations in Hepatocellular Carcinoma

A number of trials are exploring immune-oncology (IO) therapies in combination with VEGF antibodies, tyrosine kinase inhibitors (TKIs), and other IO agents as potential new strategies for patients with hepatocellular carcinoma. A presentation by Richard S. Finn, MD, during the American Association for Cancer Research Special Conference, focused on phase 3 combination studies in that setting.
April 25, 2021

UArizona researchers develop ‘Goldilocks drug’ to treat triple-negative breast cancer October, 2022

University of Arizona researchers have been working for decades to develop a drug that so specifically targets a deadly kind of breast cancer that there are little to no toxic side effects.
July 14, 2018

Wound healing genes

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July 14, 2018

Grapes activate genes

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July 14, 2018

Muscle fitness

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July 14, 2018

Alternative therapies

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April 25, 2021

Gut-dwelling bacterium singled out as the possible cause of colorectal cancer Some strains of the ‘Morganella morganii’ microbe produce molecules that are toxic for human DNA

July 12, 2018

FDA Grants Accelerated Approval to Teclistamab-cqyv in Relapsed/Refractory Multiple Myeloma

April 25, 2021

Scientific News:Recent approval of tremelimumab plus durvalumab for patients with unresectable hepatocellular carcinoma, based on results from the phase 3 HIMALAYA trial.October, 2022

Following last year’s accelerated approval designation, the FDA granted regular approval to sacituzumab govitecan to treat patients with triple-negative breast cancer. The FDA announced it has granted full approval to sacituzumab govitecan (Trodelvy) for the treatment of adults patients with unresectable locally advanced or metastatic triple-negative breast cancer (mTNBC) who received 2 or more prior systemic therapies, with at least 1 therapy for metastatic disease, according to an FDA press release.
April 25, 2021

Avelumab Plus Axitinib Shows Promising Activity in Pretreated Advanced Type B3 Thymoma and Thymic Carcinoma October, 2022

The CheckMate-816 trial is the first positive phase 3 trial demonstrating a significant improvement in pathologic response with neoadjuvant immunotherapy plus chemotherapy in resectable non-small cell lung cancer. The addition of nivolumab (Opdivo) to chemotherapy improved pathological complete responses (pCR) compared with chemotherapy alone as a neoadjuvant therapy in patients with resectable non-small cell lung cancer (NSCLC)
July 12, 2018

Therapeutic Vaccine Combination May Help Patients With Myelodysplastic Syndrome

It may be possible to vaccinate against induced NY-ESO-1 expression to produce an antigen-specific immune response in patients with high-risk myelodysplastic syndrome (MDS), according to a […]
July 12, 2018

Nivolumab Plus Chemoradiation Safe For Advanced Head, Neck Cancer

Nivolumab immunotherapy appeared safe and feasible to administer in conjunction with radiation and chemotherapy for patients with newly diagnosed local-regionally advanced squamous cell carcinoma of the […]
July 12, 2018

Phase 3 ILLUMINATE 301 Trial of Idera’s IMO-2125 Combo Therapy For Advanced Melanoma Patients

A new Phase 3 trial for advanced melanoma patients who failed to respond to Opdivo (nivolumab) or Keytruda (pembrolizumab) is recruiting participants to evaluate Idera Pharmaceutical‘s […]
July 12, 2018

Imfinzi Is First Immunotherapy Approved for Advanced Non-small Cell Lung Cancer in US

Imfizi (durvalumab) has become the first approved immunotherapy in the United States for patients with advanced non-small cell lung cancer that has stabilized. Imfinzi is a […]
July 12, 2018

Epigenetics therapy shows promise in patients with lymphoma

New compounds targeting epigenetics have shown remarkable early activity in patients with lymphoma, according to new data from the European Society for Medical Oncology
April 25, 2021

HER2-Low Breast Cancer

More metastatic breast cancer patients may be eligible to receive a treatment recently approved by the U.S. Food and Drug Administration (FDA) for a newly defined category called “HER2-low” metastatic breast cancer. October, 2022
April 25, 2021

Nanoparticles maximize cancer drug’s STING in preclinical tests October, 2022

Researchers have turned to drug delivery nanoparticles to maximize the anti-cancer STING of a molecule, pointing to a possible way to unlock the potential of a pathway that has caught the eye of the industry.
July 12, 2018

These DNA-Damaging Molecules May Be The Link Between Colon Cancer And IBD Health October, 2022

Scientists have discovered DNA-damaging molecules made by gut bacteria that may help explain why people with inflammatory bowel disease (IBD) have higher rates of colorectal cancer than those without the condition.
April 25, 2021

FDA Approves New Immunotherapy for Advanced Liver Cancer

Imjudo plus Imfinzi improved overall survival compared with standard targeted therapy for hepatocellular carcinoma.
April 25, 2021

Triple-negative breast cancer: Experimental treatment shows promise October 31. 2022

An estimated 2.3 million womenTrusted Source around the world received a diagnosis of breast cancer in 2020. That same year, about 685,000 women globally died from the disease.
June 15, 2018

New Therapies for Acute Leukemia

June 15, 2018

CRISPR-Based System Identifies Important New Drug Targets in a Deadly Leukemia-Cold Spring Harbor Laboratory

Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered a way to rein in an overactive protein that drives some aggressive leukemias. The renegade molecule, MEF2C, […]
June 15, 2018

CAR T-Cell Therapy Holds Promise for Multiple Myeloma

Cellular immunotherapies such as chimeric antigen receptor therapy are a promising approach for treatment of multiple myeloma. CAR T-cells have impressive activity against leukemia and lymphoma, […]
March 12, 2018

CAR T-Cell Therapy Holds Promise for Multiple Myeloma

Cellular immunotherapies such as chimeric antigen receptor therapy are a promising approach for treatment of multiple myeloma. CAR T-cells have impressive activity against leukemia and lymphoma, […]
March 8, 2018

CRISPR-Based System Identifies Important New Drug Targets in a Deadly Leukemia-Cold Spring Harbor Laboratory

Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered a way to rein in an overactive protein that drives some aggressive leukemias. The renegade molecule, MEF2C, […]
March 7, 2018

New Therapies for Acute Leukemia

While 2017 was a milestone year for acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL), where a combined 7 agents were approved by the FDA, […]
March 6, 2018

Epigenetics therapy shows promise in patients with lymphoma

New compounds targeting epigenetics have shown remarkable early activity in patients with lymphoma, according to new data from the European Society for Medical Oncology
March 1, 2018

Phase 3 ILLUMINATE 301 Trial of Idera’s IMO-2125 Combo Therapy For Advanced Melanoma Patients

A new Phase 3 trial for advanced melanoma patients who failed to respond to Opdivo (nivolumab) or Keytruda (pembrolizumab) is recruiting participants to evaluate Idera Pharmaceutical‘s […]
February 21, 2018

Imfinzi Is First Immunotherapy Approved for Advanced Non-small Cell Lung Cancer in US

Imfizi (durvalumab) has become the first approved immunotherapy in the United States for patients with advanced non-small cell lung cancer that has stabilized. Imfinzi is a […]
February 15, 2018

Nivolumab Plus Chemoradiation Safe For Advanced Head, Neck Cancer

Nivolumab immunotherapy appeared safe and feasible to administer in conjunction with radiation and chemotherapy for patients with newly diagnosed local-regionally advanced squamous cell carcinoma of the […]
January 29, 2018

Therapeutic Vaccine Combination May Help Patients With Myelodysplastic Syndrome

 It may be possible to vaccinate against induced NY-ESO-1 expression to produce an antigen-specific immune response in patients with high-risk myelodysplastic syndrome (MDS), according to a […]
January 26, 2018

Venetoclax Active in CLL Progressing After Idelalisib

Venetoclax had promising clinical activity, with a high objective response rate among patients with relapsed or refractory chronic lymphocytic leukemia (CLL) previously treated with idelalisib, according […]
January 23, 2018

Engineered Tumor-Specific T Cells May Help Relapsed Hodgkin Lymphoma Patients

 It may be possible to treat patients with relapsed Hodgkin lymphoma (HL) with a new engineered T-cell approach that is less toxic and does not require […]
January 23, 2018

Nivolumab Plus Ipilimumab Offers Improved Survival Outcomes in Certain Metastatic CRC Patients

The combination of nivolumab and ipilimumab yielded high response rates and encouraging survival outcomes in a cohort of previously treated patients with DNA mismatch repair-deficient (dMMR)/microsatellite […]
January 18, 2018

MHOA Selected as a Recipient of the COLA Laboratory Excellence Award

This award signifies MHOA’S laboratory’s commitment to performing quality patient testing and overall laboratory practices. The Laboratory Excellence Award is achieved by those laboratories that are […]
January 1, 2018

New Treatment Paradigm Supersedes ABVD in Advanced Hodgkin Lymphoma: The ECHELON-1 Study

Phase 3 results from the ECHELON-1 study, presented at the 59th Annual Meeting & Exposition of the American Society of Hematology, showed superior modified progression-free survival […]
December 19, 2017

Copanlisib May Benefit Patients with Relapsed or Refractory Indolent B-cell Lymphoma

Updated analyses are validating the efficacy of copanlisib in the treatment of relapsed or refractory indolent B-cell lymphoma. Investigators reported at the 2017 annual meeting of […]
December 15, 2017

FDA approves first treatment for breast cancer with inherited genetic mutation

The U.S. Food and Drug Administration today expanded the approved use of Lynparza (olaparib tablets) to include the treatment of patients with certain types of breast […]
December 12, 2017

Mogamulizumab May Benefit Patients with Cutaneous T-Cell Lymphoma

Clinicians may soon have a valuable new therapeutic option for treating patients with cutaneous T-cell lymphoma (CTCL). Results of a randomized phase III study presented at […]