Treatment for Ovarian Cancer: the treatment for ovarian cancer is based on the stage of the disease and the extent that the malignancy has spread. The standard treatment for ovarian cancer consists of debulking surgery followed by six rounds of chemotherapy.
The chemotherapy treatments may be given IV, or IP (Intraperitoneal Chemotherapy places the medicine directly into the peritoneal area through a surgically implanted port and catheter).
Other drugs, including angiogenesis inhibitors and targeted therapies, may be recommended either in conjunction with chemotherapy or as single agents. Hormone therapy, usually for stromal tumors may include luteinizing hormone releasing hormone agonists, aromatase inhibitors, and tamoxifen.
Stage I: cancer is confined to one or both ovaries. Treatment for women with stage I cancer have a total abdominal hysterectomy, removal of both ovaries and fallopian tubes, and biopsies of lymph nodes. If the tumor is high grade, surgery may be followed by chemotherapy.
Stage II: cancer is present in one or both of the ovaries and has spread to the uterus and/or the fallopian tubes or to other sites in the pelvis. Treatment is usually a hysterectomy and bilateral salpingo-oopherectomy (removal of the ovary and fallopian tubes) with tumor debulking followed by combination chemotherapy with or without radiation
Stage III: cancer is present in one or both of the ovaries and has spread to lymph nodes or other sites outside of the pelvis but is still within the abdominal cavity, such as the surface of the intestine or liver. Treatment is the same for stage II, including surgery and combination chemotherapy.
Stage IV: cancer is present in one or both ovaries and has spread beyond the abdomen or has spread to the liver. Treatment is usually surgery, followed by chemotherapy.